Your Name: Ho Kwong Li

Theme: Lymphoma

 

OPTION LIST

 

A

Antiretroviral & IFN alpha

I

Rituximab

B

Bone marrow transplant

J

Surgical excision

C

Chemoradiotherapy

K

Watch & wait

D

Chlorambucil

L

 

E

Fludarabine

M

 

F

Imatinib

N

 

G

Melphalan

O

 

H

Radiotherapy

P

 

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1. A 32-year-old man presents with cervical and inguinal lymphadenopathy, intermittent fever and drenching night sweats. Lymph node biopsy shows Reed Sternberg cells.

 

 

2. A 42-year-old man presents with painless enlarged left axillary lymph nodes with no other symptoms. Histology shows a follicular pattern with “cleft” white cells in the blood film.

 

 

3. A 64-year-old retired secretary is diagnosed with relapsing Non-Hodgkin’s Lymphoma. What is the most appropriate 2nd line treatment since investigations of the lymphoma show it to be CD20 negative?

 

 

4. A 57-year-old Caribbean man presents with generalised lymphadenopathy, cutaneous lesions, bone lesions and hypercalcaemia. He is also noted to have an enlarged liver and spleen. Serology shows him to be positive for HTLV1.

 

 

5. A 65-year-old lady presents with enlarged cervical lymph nodes and splenomegaly. Otherwise she is well with no other abnormalities. Histological investigations have confirmed a diagnosis of indolent Non-Hodgkin’s Lymphoma.     

 

 

 

ANSWERS

1. C

2. H

3. E

4. A

5. K